Regadenoson and exercise myocardial perfusion imaging: The courtship continues

Regadenoson for myocardial perfusion imaging: Is it safe?

Regadenoson is currently the most widely used pharmacologic stress agent for myocardial perfusion imaging (MPI) with millions of doses administered annually in the US. In November 2013, the US Food and Drug Administration (FDA) issued a Drug Safety Communication warning health care professionals of the rare but serious risk of heart attack and death with use of either regadenoson or adenosine. ...

Serious complications associated with regadenoson administration for myocardial perfusion imaging

The Editorial by Hage and Iskandrian regarding ‘‘Serious complications associated with regadenoson administration for myocardial perfusion imaging: A commentary’’ (September/October 2014 issue) includes a table as a guide for serious complications associated with regadenoson administration. In the table, the authors reported whether or not each listed event occurs with exercise and/or adenosine...

Regadenoson Cardiac Stress Myocardial Perfusion Scintigraphy

[Regadenoson as a new stress agent in myocardial perfusion imaging. Initial experience in The Netherlands].

OBJECTIVE Regadenoson is a recently approved selective adenosine-2A receptor agonist to induce pharmacological stress in myocardial perfusion imaging (MPI) procedures using a single bolus injection. MATERIAL AND METHODS We included 123 patients referred for MPI because of suspected coronary arterial disease (CAD). Of these, 66 patients underwent a regadenoson stress test and 57 patients under...

Detection of obstructive coronary artery disease using regadenoson stress and 82Rb PET/CT myocardial perfusion imaging.

UNLABELLED Our objective was to study the diagnostic performance of regadenoson (82)Rb myocardial perfusion PET imaging to detect obstructive coronary artery disease (CAD). METHODS We studied 134 patients (mean age, 63 ± 12 y; mean body mass index, 31 ± 9 kg/m(2)) without known CAD (96 with coronary angiography and 38 with low pretest likelihood of CAD). Stress left ventricular ejection fract...